Do you have a hotel you deal directly with on business? We use the Hilton family of hotels for 98% of business and personal travel. Sometimes the hotel itself (not online, not priceline or discounters) will cut a good break for you. Just ask for the sales dept.
I do this alot because my hubby is in Houson 3-4 times a month so I negotiated a deal much lower than the rack rate and we as long as he stays a minimum of nights until Dec 31, we have that rate.
Can't hurt to ask. Also, check the suite hotels such as Residence Inn (a Marriott property) which are basically mini apartments.
Good luck!!