M.G.
Well I don't have twins so can't share that experience.
I do know I carried differently and had different symptoms with the different genders.
My headaches, spotting, bump, sleep, moods, fatigue, how much I bloated was very dependent on the gender. Even my hair was different.
I also was more fatigued and had headaches the older I got. Part of that I think is just age (and the peeing) and part of it is you have little ones already to care for.