It depends on the dog and how he travels if I would you the medication. We have moved a few times, our dog is fine with travel as ia one of our cats so no meds for them. The other two cats get medicated since one is very nervous and one gets sick in the car.
Test the medication out before you go ifyou think you will need it so you can see how it affects your dog. It took three tries and two meds to find the right one for one of our cats, the other anything works.
Also decide before hand if possible since some meds need to be in their system for thirty minutes to an hour before stress to work the best. You may change your mind and give it when needed too.
Safe travels!