L.R.
This is about much more than "Adderall and preganancy." Before she does anything else, she needs a new doctor NOW (preferably one with lots of experience with these drugs) and she also needs a supportive ob/gyn who will work with that new doctor closely and directly. If she is "weaning herself off Wellbutrin" without a doctor's close supervision she could be setting herself up for serious problems. Mamas are a big support but are not medical professionals and there are a host of medical issues here with which she deserves the best possible help. If her meds are that important to her work, she may want to consider really sitting down with her husband and doctor and working out whether, when and how to take time off work to get pregnant and have the pregnancy. And she already knows that the consequences could be "a major change in her personality" that could affect her marriage, the friendships that give her support, etc. All the more reason to get serious professionals lined up before she takes herself off any meds and to be totally up front with her new doctors. She has a terrific and supportive friend in YOU and maybe you can help her get the professional backing she needs. And her husband must be on board too, and there for the doctor visits, so she alone doesn't hear the advice -- she will be worried and worked up and it's good to have another pair of ears there! Good luck. You're a great friend.