When it comes right down to it the only choice you have is to put a patch on the inside or toss them then it makes it an easy choice. They can become the "run errands to Walmart" jeans...lol.
Take some older jeans and cut out a couple of squares that would more than cover the worn area.
Use lightweight Heat and Bond and adhere the right side of the patch to the wrong side of the thigh area. This puts the same texture to the outside of the pant. Often people will think that wrong sides go together but I think putting the right side facing out will make any holes blend in better since both the patch and the jeans have the same fabric facing out...clear as mud?
My friend grew up in an affluent California home. Her mom was a Vogue model and dad was, well, he had a finger in most pieces of the pie in movies, plays, all sorts of things, I guess he was an entrepreneur. She had governesses and nanny's and can remember Clark Gable eating dinner at her house numerous times....
Her mom would make her stand straight up, with a piece of paper between her thighs. If the paper didn't fall down straight away her mom told her she was fat. She was a skinny kid with shapely thighs. It was torment.
My sister is 4'11" and at her highest weight was 9 months pregnant at 125. She is normally around 100-110 lbs and her thighs have always touched even on a thin day.