A.H.
Depends on the offense...for poop on me, I'm changing that every time. Just yuck. For puke, yeah I'm changing that one too. Pee as well. I guess any bodily fluids get on me I will change my clothes. I have had days before where I noted that both myself and the baby were on our 5th outfit of the day (including the pjs we initially changed out of). And that's back when we shared laundry with 2 other apartments. ;/
If one of the kids spills some food on me and I can decently wipe it off, I might roll around the house with a bit of a stain until I need to leave the house.