Congratulations on your pregnancy! I'm sorry that your relationship with your best friend doesn't just increase the joy of it. But things are what they are, so just go from there.
You have had such good response from moms who can really see what your friend must be feeling. I imagine that helps you to take her remarks less personally and maybe even to feel for her, which also can decrease the pain that you feel.
You didn't say whether you responded to the hurtful things she said about your trying again. Of course you are right about how untrue every one of them is. There is great power in just saying simply, "It hurt me very much to hear (the things that she said that caused the pain go here)". No matter what she says in response, you will feel a lot of freedom in your feelings from just saying it out loud to her. You will likely find then that it is easier to consider how you want to tell her about your pregnancy. I would imagine, though, that it will be in another conversation at a later time. I don't know that for sure, but I personally can only handle so much emotion at a time. You can just feel it out.
I don't know if this is what you are looking for, but I think I was mostly responding to your question, "Is it worth it to say anything to her?" You say repeatedly what a good friend she is, so I assume that you want to really work for this relationship. And in the little bit of wisdom old age has provided me with, I truly believe in this concept of speaking your hurt. If you decide you believe in it, too, you may find it coming in handy more than once as you travel these very emotional waters with her. Remember, though, that you are NOT accusing her. You are just sharing what you feel. Your feelings are not her fault, they belong to you. But that is another subject altogether...