Your son is quite young for what you are asking, and he may just be still getting control, however, you need to know whether this is the case or something with a medical reason or just the difficult issue of night-time bedwetting. Called nocturnal enuresis, this sort of wedwetting is often an inherited condition, father to son, or even passed through the mother's side of the family. Ask family members to be very truthful with you. In boys (such as one of mine) this was certainly the case although we did not really investigate until he as about 6, and it was a very tough situation. Take your son to a pediatric urologist as well, just to be sure there is no other reason, but prepare yourself for a longer ride with this, and PLEASE stop making him feel your frustration---believe me, he is hiding his own! We tried all the things you have and then some, but finally decided by age 7 that none was not going to work. We were advised to avoid the medications which suppress urine production, unless absolutely necessary (for a very important SINGLE night--no long-term use like for camps or travel). It took until probably 11-12years for this boy to be truly safely dry at night. We struggled to hide our frustration, but it was was it was and you know that they will be dry eventually. Praise for small successes and making them a part of their own help is crucual with age....but certianly not until about 6-7. Use of small adult size Depends were helpful for some containment, but as you have already discovered, as their baldder size grows so does the urine volume....Basically, a specially made up bed was the answer to containing the mess and our son's ability to help himself. First, put waterproof ZIPPERED covers on the mattress and pillow(s), then make the bed with a fitted under sheet, a blue removeable waterproof pad that tucks in only on the sides (like a wider version of those used in hospitals) and then a soft second flat sheet lightly tucked in as if fitted on top. Duvet or comforters or blankets need to be low volume for constant washing. When he wets at night (or if he only discovers it in the morning) he should be taught how to drag all wet stuff off his bed and throw it in the nearest bath-tub (hopefully not far from his bedroom). If this is not how your house is configured, then a large plastic bucket in the hall outside his door would work. New sheets , a clean pillow and a clean blanket should be available on a chair in his room at bedtime every night. If he wakes in the night soaking wet, he can dump all the wet stuff and grab all of parts from the clean stack and be back in bed to get some rest in no time. As he gets older you do not want to be wakened, yet is is essential he get adequate sleep too, and he will feel he is handling things for himself, but more, for YOU. He is very aware he is causing grief for everyone and will definitely feel badly even if he does not seem to show it. Yes this takes huge effort on your part, but don't forget: on his too, and he is not happy with himself----BUT----should not be blamed as if he is unable to follow some simple command. You should also be considering how difficult this will remain for him through grade school when he is invited to other friend's houses overnight. Just be sure he is confident, has pull-ups with him (they now make some that look like underwear for kids) and, this is crucial, that you talk to the mother of the invitee. Let her know this is a problem and ask if she is OK with it, protecting both her bedding as well as your son's pride. There are loads of ways to get her son and yours up and out of the sleepover bedroom for pancakes or fun video before wetting can be discovered, but you owe it to a host family not to have their bedding or other furnishings ruined. We never found anything but wise sympathy and delight at having our son as a guest, even under these trying (for HIM) conditions. Have as many sleepovers at your house so you can manage the mornings. If this in inherited bedwetting, you need to have a plan now---your son will be able to help you in a few years, but the burden will always be more his than yours. good luck.