We've done the drive with tots in tow and it can stretch to 9 hours once you count all the stops to give the kids a break. Honestly, however, our flights down there haven't been any more pleasant. There are long lines in the airport, and ALWAYS delays in that route (have no idea why, but we've had at least an hour delay every time). At least on the road trip we can plan in something fun. If you have a portable DVD player, you should be able to survive the long, empty drive between San Antonio and Corpus. Before that, we usually stop in West or Waco, and there are great parks in New Braunfels/San Marcos for kids to run off some steam. Other times, when there might be a melt down in the car, we have been known to stop at roadside picnic areas just to run circles around the car :-).