R.,
I suffered with nausea and chronic vomiting daily for the first 4-5 months and then just sporadic times through the 6th. It's horrible, and I am so sorry that you are going through this. I don't think there is a magic bullet that will work for everyone, so you are going to have to try different foods until you find something that's acceptable. I do know that I and several other women with this problem could eat a McDonald's quarter pounder w cheese but nothing else on it (no pickles ketchup etc). I found that on my own, but when I asked my father who is an OB/Gyn, he said some of his patients told him the same thing. I personally know of 4 other women who told me that McDonalds worked through their nausea. I felt guilty about eating it because it was "bad for me" but Dad said calories at this point are the most important. Also, he said basically as long as you are getting your vitamin down, you can pretty much live on bread and water and the baby will still grow. The baby physiologically has priority over you and will deplete your body of nutrition before it goes without. So, I pretty much tried to eat if I could during the day, and if it didn't work, then I defaulted to McDonalds for dinner to try to keep my calories up. I lost 20 lbs in the first 4 months.
As far as things that helped me, I found I could eat sour things like plain yogurt and pineapple. I'm at 8 months now and still cannot do things like tomatoes though. Also, I found that chewing on candied ginger can help (sometimes at Trader Joe's but otherwise you can get it in the spice aisle at the grocery store). Preggie Pops (or Drops if you don't want to walk around with a lollipop stick hanging out of your mouth) gave some minor relief. Natal B sour apple lozenges were a little more effective instantaneously, but didn't last as long. Both are available at Babies R US. Also at Babies R Us was a good gummy pre-natal that I could actually keep down. You don't need to worry as much about iron until late 2nd trimester, and that this usually the element in prenatals that can make you puke or increase your constipation.
Regarding the drugs...ok I will admit that I tried all of them, and really NOTHING was super, but since I am a surgeon who prescribes all of these things post-op for patients, I decided to try them all when I really got desperate. Here's how they each work:
1. Reglan-It's not that often prescribed in morning sickness, but initially this was my go-to med. It increases the propulsion of the GI tract and helps things move along. One of the proposed biggest culprits of morning sickness is the effect of progesterone on bowel. It basically slows it was down and doesn't keep things moving. This allows the bowel /stomach to swell like a water balloon, and that mechanical stretch can be painful and nauseating. Your body will cause you to get rid of the contents, ie puke. Supposedly the evolutionary idea behind the work of progesterone is that is slows the transit of food through the GI tract and gives your body every chance to extract nutrients out before it hits the large intestine and becomes waste. To me, the effect was vomiting everything I ate, avoidance of food as well as severe constipation. Reglan wasn't a magic bullet,. but it did make the first significant dent in starting to get things under control for me.
2. Zofran/Kytril/Anzemet/anything generic that ends in -setron-These are a newer and sometimes more expensive kind of antiemetic that work centrally in your brain helping dampen the nausea signal coming from your gut so that you don't recognize it as much. These are totally safe in pregnancy and most patients will tell you that this is "the best." When I was in medical school, Zofran was so expensive, you could only prescribe it in the hospital if a patient didn't get relief from anything else. Zofran helped (not cured) things for me in months 4-5 are the slow motility problems were less prevalent and reglan wasn't working so well. The biggest bonus that I see with it is that there are no sedative side effects.
3. Phenergan-This is a cheap, widely available older anti-emetic that works centrally in the brain as well. It has some properties that are similar to benadryl, so you will get sedated from this. Some patients love it, some don't notice any effect. Almost everyone gets really drowsy. I did use this to try to get some sleep at night when I was too nauseated to sleep. It sorta helped, but it certainly wasn't awesome. Again, this one is OK to prescribe during pregnancy, but I don't recommend taking it any time other than when you are at home and not doing anything.
4. Sleep aids-Some people will swear by unisom or tylenol PM or whatever esp at night to get some rest and quell nausea. Don't waste your money, and read the back of the packages. All that Unisom is is really expensive benadryl. I think something upwards of 90% of over-the-counter sleep aids are just diphenhydramine (generic Benadryl), including tylenol PM, unisom, any allergy medicine with PM formulation and all of the cold remedies that advertise "so-you-can-rest-medicines." Benadryl did help me sleep for a while, but the best thing to do is buy the store brand diphenhydramine.
Hope that helps. Good luck. It will get better.