Yay for you!!! We just got back a few weeks ago from leaving our kids for 10 days. We went on a cruise and left them with my SIL for 1/2 the time and my mom for the other half. It was so hard on me, but they were more than fine...serioulsy. My kids are 3 and 16 mos. It was a little harder on the baby b/c he just didn't get it. One day we were here and then we weren't. But at the same time, he has zero concept of time, so then we were back! ;) The first 4 days we called in my daughter was too busy to talk to us...my SIL asked if she wanted to talk and she said, oh no thanks...and went on about her day! LOL! DO NOT feel guilty! You deserve to go and have fun and you WILL!!! The worst part is the anticipation of leaving. One b/c you feel guilty and two because you have so much to do, but I promise once you touch down in Italy you will put on your vacation attitude and it will be great! Here's a few things we did if you want some tips...
About a week or two before we left I played it up to my daughter that SHE was going to be on vacation too. They would do fun things, eat treats, etc. etc. I also told her she would need to help take care of her little brother, and she loves that, so that helped too. We also put international calling on our phone...if you don't have it, get it. You can just do it for a month or even a few weeks I think. Also, make sure you get a document that gives over the right to make medical decisions to the grandparents. You will either have to have it notorized or we downloaded one from a legal website, I think it cost like $15 which is a little more than a notary, but easier since I didn't have to go anywhere. The best thing I did was leave presents for them to open every morning. I picked up a bunch of random things and put them in manila envelopes. I got things like candy for one day, cars and little dolls, a DVD, a gift card to McD's, balloons, etc. I also printed off pictures of us and the kids and put 1-2 pictures inside the envlelopes. I got one of those cheapo photo books that are just clear and made a cute cover for it. I put that in the first envelope and they got to put all the pictures in it every day plus they had pictures of us to look at. I decorated each envelope and put the date on it. It worked out really well b/c the 3 y/o was way into presents, plus it gave her a way to count down the days until we came home. Our caregivers said this was great for them too. We agreed to check in once a day, usually in the morning b/c we figured everyone would be home then. It was super fun and we can't wait to do it again! It will be okay, and trust me, you'll be more worked up about it than the kids!
Oh and I also wanted to add that my daughter was so glad we were home and for the first day or two she kept telling me I'm so glad you're home, and then on third day she stated that daddy and I could on vacation again, she was fine! LOL!