Think outside the box. What are you good at? What do you love?
Keep in mind, working from home is "work".... If you work for another company, you're expected to have child care, no dogs barking, etc. It's a job and requires self discipline.
We run our company from home which is in the raw materials industry, niche market. We have warehousing and trucking set up in Dallas.
It is a lot of work. You have to have strong work ethic, self motivated and be ready to accept risks
You'll get plenty of responses for mlm and direct sales. That works for a lot of people but keep in mind that a lot if people are also very turned off by parties, recruiting, etc.
Good luck