Hi S.,
I just went through this with my four-year-old and have finally had a stretch of three months with no nighttime accidents. Here is what I did.
1) Took him for a chiropractic adjustment once a week. EVERY time he received a (gentle) adjustment to his hips, he would go several nights with no accidents. If the hip bone is even slightly out of alignment, it can interrupt the nervous system's ability to send a message to the brain saying "wake up! your bladder is full."
2) At the chiropractor's suggestion, we also stopped letting him wear crocs for shoes. She said they didn't support his hips well enough. He needed to be in sneakers with good arch support.
3) We woke my son every night between 10:30-11 and again around 5am. We would take him to potty. If he just couldn't go (late evening), we would wake him 1-2 hours later.
4) We limited his drinking after 7pm.
5) We also eliminated dairy from his diet. For some reason, dairy effects certain kids. Eliminating it from the diet can sometimes take care of the bedwetting with no other intervention.
After a few months of this routine, we began eliminating the 5am potty run. Now we just take him before we go to bed. It's almost like we trained his body to go at a certain time. I also think that after the regular chiropractic adjustments, his hips began to stay in the correct position. He now goes every night around 11ish (we wake him). He does still sleep on a crib pad that is placed over his sheets, but he hasn't wet it in months.
I hope this helps. If you need a recommendation for a good, child-friendly chiropractor, let me know. I know several in Jax. :0)
Take care,
M.