E.S.
Organization is the key, I have a home daycare and I'm studying online to get my degree for Early childhood education, here is how I do it. Wake up at between 6:15-6:25
get ready for my day, put everything out that I will use that day for the children,then I start a load of laundry in the washer,after that I study online for 30minutes until the first child arrives at 7:30-7:45, I give her breakfast, wake up my daughter and dress, feed her. And then I do circle time, preschool curriculum and follow the schedule for the children, after lunch I read them a story and they nap for at least 2 hours.During that time I do a quick cleaning of the mess we made doing crafts,and eating, wash dishes,clean their bathroom,sweep & sanitize toys and set out the snacks for after they wake up and any other activity we might do later. And I put in the dryer the clothes that I washed in the morning, and finally I study online until they wake up. Again I follow my schedule with the children until my last child gets pick up at 6:00-6:10. After that I clean the playroom, sweep, mop floors,sweep and clean kitchen and living room, make dinner, fold the clothes that where in the dryer. And after dinner when my husband and my daughter have gone to sleep, I study for another 30-45 min. but not too late so I can get up in the morning again on time.
So like I said it's all about having a schedule and dividing the chores for each day, you can do one load of laundry everyday so it does not build up, clean bathrooms and dust another day, and so on if you let the work pile up it's harder to keep up and will take off precious time needed for other important things.
It's possible to finish school and stay at home and work, but you have to be consistent and gather help from your own family, for example your 6 year old after she finishes her homework can help with folding the laundry and putting it in it's place, pick up her room make her bed,your husband can spend time with the children maybe after dinner, play or read to the children, while you get some work done.
And if that's not enough time, you can always send the two little ones for two hours during the day to part-time daycare look for ones in your area that offer those services or hire a nanny for a few hours during the day. I hope this helps you, I know it can be difficult but it is not impossible!
Oh I almost forgot always take a day (Saturday/Sunday)to unwind,wake up late, no schedules during that day just and your family, go out to eat, or to the park/movies, and have fun, that day of relaxation will help you keep up your schedule during the week without going insane!