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Daughter with Terrible Diaper Rash

My daughter has had a very bad diaper rash that keeps coming and going. I have tried a couple of things but nothing is helping in the long term. She just squeals when I try to clean her up or when she is going to the bathroom. Any suggestions on stuff that worked for you? I am pretty sure it is not a yeast infection because I checked it out online (what it looks like and other). Thanks