R.B.
It's gonna be fine. The adjustments will probably be harder on you then your kids.
1. People who work 40 plus hours a week the time out of their work day to go to dr appts now and then. Plan these around your slower months or weeks at work in addition at the beginning of the day, end of the day or lunch hour as best you can to minimize the impact.
2. Sick kids - since my spouse and I have fairly equivalent earnings and work demands so we split the responsibility. We take into consideration who has the most pressing need to be in the office. Some times, one of us can work from home. Sometimes we split the day: ie he goes in form 7 - 1 and meets me at home I'm at work around 1:30 and stay still 8 or whatever. Since we have 3 kids it's like dominos when one get sick another is right behind so we've also alternated days.
Someone will probably be offended by my comment so let me clarify - I personally would give more priority to the career that is the bread and butter to my family. The career that is the icing the cake would take a back seat in my house. So that is not to offend anyone to me it is just logical and pragmatic. Sometimes I've worked part time and that meant I took on all the responsibility of appts and sick kids.
3. Romance and social life - this will probably be a big adjustment especially if you both have jobs that actually require more than 40 hours a week. My biggest advice. Schedule a date night. It doesn't have to be expensive - it could be a date at home but it set aside time just for the two of you. Make it regular as you will probably lose out on regular time you currently have M-F together.
4. Housework etc - prioritize and outsource where possible. Actually your kids are old enough to do a lot of the housework. Hire someone to do the deep cleaning 2 x a month if you can afford it.
5. Make some career mom friends. Juggling a full time job and a family does get challenging at times. Sometimes I wonder why I do it. But I love having a career. I love my career mom friends as an outlet and knowing I'm not alone ;)
Good luck! I hope this new endeavor enriches your life and your families.