Been there, done that. Completely NOT worth it in my personal experience. My time = $$ I don't like my home being checked out by strangers.
Our neighborhood HOA puts one on in the spring and fall and I ( along with the majority) lock everything up because there's lots of traffic in our quiet, nice neighborhood and some people using the "sale" to check out the homes.
Take into consideration that no matter how almost new or good condition something is...... people want it for nothing. If you ask $1 they want it for a dime.
I found it insulting and I shut my sale down because I came out better to donate to someone I know appreciates it vs someone trying to get me to just give it to them. Ex: Abercrombie jeans new with tags $50, I asked $15, I was offered $2. No thanks. I told the people to leave my property.
Not to mention the safety issues of having your house cased out by people who aren't really shopping the sale.
IF you do it, make sure your set of eyes is not the only set watching nonstop. It's amazing how crappy some people truly are.
We had a couple of neighbors who live in the center section area of the neighborhood try it out to get extra money and they ended up wiped out within a couple months. Police believe it was from garage sale posts.
Be careful whatever you choose.
Personally... I say no. I don't mind taking my things to the women's shelter, goodwill or having goodwill pickup so I know my things are appreciated elsewhere.