Your post is about fulfilling yourself, which can happen in a number of different ways. If you know that what you want is a career, then I suggest prioritizing what the ideal career for you would be. I have a stack of cards that each list a value (prestige, money, friendship, family...), and it has helped me to put them in order each time I'm thinking about a major change. This will help you to determine what it is that you're looking for in a career (or some other change, if you're not committed to that path). I think the reason a lot of people aren't fulfilled is that they're doing what they think they SHOULD be doing even if it's in conflict with their personal values and priorities. Once you have a sense of what you want (e.g. something with flexible hours and people you enjoy or something that fosters your creativity or something that earns you respect from others and a decent wage), you can search more effectively for choices that will help you to feel better about yourself and then put together a plan to make it happen...
P.S. If you want the full list of values from the cards, just shoot me a quick message. I'd be glad to pass them along to you.