Dear D.:
I feel your pain! I went through that when I began menopause (didn't realize at the time how many suicidal thoughts I was having!).
Depraloft (a holistic antidepressant that you can get at some health food stores and places like Pharmacopia) and extra Gara (B-vitamin, excellent for stress) helped me. Took a couple of days to really feel relief beginning, but the Gara was effective at lessening the knot in my stomach.
I also make a product in my Essential Oil line that I call "Flash Relief". It's great for calming hot flashes, but also helps with those hormonal imbalances that come with PMS, Menopause and other joyful female times. Let me know if you'd like more information.
And most importantly, take some time for yourself to just be alone and quiet. Soaking in a tub with some therapeutic bath salts (yes, I do make these, too) in a dark bathroom with perhaps some soft music in the background can be very healing. Just make sure the family knows that you are totally off-limits while you take your time-out.
Hang in there!
V. T